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Osteoarthritis can also be modeled in mice by destabilization of your medial meniscus by surgically sectioning a ligament in the joint. The CB2 receptor agonist HU308 reduced joint harm inside the DMM osteoarthritis product, Whilst CB2 (−/−) mice designed a lot more joint harm than wild- sort mice (Sophocleous et al, 2015).Psychotropics are a w